Saguaro

ChromaLive Non-Toxic Dye

Generate New Lead Compounds Faster

Dying HeLa cells stained with ChromaLive and captured on Yokogawa CQ1 Imager

A First-of-a-Kind Dye

ChromaLive

Unlock new dimensions for evaluating drug performance in
high-content screens

Unlocking Time and Scalability

1

Non Toxic

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Unaffected gene expression enables live cell imaging over weeks

2

Multiplex

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Quantify broad ranges of cell states, or hint at drug mode of action

3

Automation Friendly

One-step, mix-and-read dye that does not fluoresce in media

Capture more with one dye

  • More timepoints
  • More phenotypes
  • More throughput

Get in touch

Reach out to learn more about ChromaLive

 

Applications

Mechanism of Action

Just like cell painting, MoA of new compounds can be predicted by comparing with compounds of known MoA. However, ChromaLive was found to improve robustness of MoA predictions, shorten turnaround time, and elucidate time-dependent phenotypic shifts.

Toxicity Testing

Identify toxic concentration thresholds of compounds with dose-response assays. Distinct cell death mechanisms triggered by compounds can be quantified by comparing their phenotypic profile to that of  compounds with known toxic effects.

Time-Lapse Assays​

Incorporate the dimension of time to bring new insight into the mechanisms of compound, genetic, or pathological perturbations.

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