In this how-to-guide, we report the design of a new high-throughput screening (HTS) workflow for non-toxic live cell painting, which allows scientists to capture new profiling data at scale, with toolsthat preserve cell physiology. Our...

  ChromaLIVE+ ER is the latest and highest performing Cell Painting technology that pushes the boundaries of image-based profiling. Building on our ChromaLIVE technology and our endoplasmic reticulum dye ER-LIVE, this powerful, non-toxic dye combination...

ChromaLIVE™ est le colorant non toxique idéal et une technologie de pointe pour le profilage basé sur l’image. Contrairement à la méthode de "Cell Painting", qui nécessite l’utilisation de plusieurs colorants et la fixation des...

Découvrez ChromaLIVE™ Deep Red, identique à notre ChromaLIVE original, mais avec des propriétés spectrales différentes, permettant une compatibilité avec le colorant nucléaire non toxique NucleoLIVE. Apprenez son protocole simple, sa compatibilité instrumentale et comment optimiser...

ChromaLIVE™ est un colorant non toxique pour cellules vivantes, fonctionnant selon un mécanisme unique de rotor moléculaire. Il permet un profilage phénotypique à haut contenu sans perturber les cellules. Contrairement aux colorants traditionnels qui se...

  This reference guide outlines the Key Considerations for Live Cell Painting (LCP) screens applied to High-Throughput Screening (HTS). LCP offers superior biological relevance by capturing cells in their most physiological, unperturbed state, compared to...

Introduction The search for new medicines has long been dominated by two main strategies: target-based and phenotypic screening. While target-based approaches focus on a single, well-understood biomarker, phenotypic screening takes a broader view, testing drugs...

Context Multiple drug discovery and academic groups have adopted image-based profiling in the last decade for many good reasons: akin to other profiling methods like transcriptomics or proteomics, it captures rich biological data that’s overlapping and...