SLAS poster 2025 - Deconvoluting cell death mechanisms with ChromaLIVE™ at Merck: a comparison with cell painting

SLAS poster 2025 - Deconvoluting cell death mechanisms with ChromaLIVE™ at Merck: a comparison with cell painting

Explore our collaboration with Merck! Our poster, "Morphological Profiling: Comparing Cell Painting and Live Cell Painting for Deconvoluting Cellular Toxicity Kinetics and Types of Cell Death Mechanisms in High-Throughput", showcases ChromaLIVE™.

This study, utilizing Merck's state-of-the-art live-cell imaging platform, compares cell painting with our data-rich, non-toxic dye for characterizing cellular death mechanisms. It demonstrates how live cell painting with ChromaLIVE™ provides impactful insight into the kinetics of compounds inducing cell death, allowing observation of distinct cell death signatures over time without the need for fixation and washing at each time point.

This powerful and scalable approach is ideal in high-throughput formats , offering significant advantages for morphological profiling in live cells and understanding drug mechanisms.