SLAS poster 2025 - Deconvoluting cell death mechanisms with ChromaLIVE™ at Merck: a comparison with cell painting
Explore our collaboration with Merck! Our poster, "Morphological Profiling: Comparing Cell Paintingand Live Cell Paintingfor Deconvoluting Cellular Toxicity Kinetics and Types of Cell Death Mechanisms in High-Throughput", showcases ChromaLIVE™.
This study, utilizing Merck's state-of-the-art live-cell imagingplatform, compares cell paintingwith our data-rich, non-toxic dye for characterizing cellular death mechanisms. It demonstrates how live cell paintingwith ChromaLIVE™ provides impactful insight into the kinetics of compounds inducing cell death, allowing observation of distinct cell death signatures over time without the need for fixation and washing at each time point.
This powerful and scalable approach is ideal in high-throughput formats , offering significant advantages for morphological profiling in live cellsand understanding drug mechanisms.