How does ChromaLIVE™ non-toxic dye work?

How does ChromaLIVE™ non-toxic dye work?

ChromaLIVE™ is a non-toxic live-cell dye that operates through a unique molecular rotor mechanism. It enables high-content phenotypic profiling without perturbing cells. Instead of binding to specific biomarkers like traditional stains, ChromaLIVE passively incorporates into lipid membranes, revealing the full morphology of live cells in real time.

Its dual fluorescence channels respond to environmental changes within the cell, including stress, death and metabolic activity. This makes it ideal for brightfield-compatible live-cell imaging, cell painting and cytotoxicity assays in 2D and 3D cultures.

Thanks to its fluorogenic properties and membrane-specific localization, ChromaLIVE™ offers a powerful alternative to conventional dyes for image-based analysis and phenotypic screening in living cells.