Protocol - ChromaLIVE™ non-toxic dye

Protocol - ChromaLIVE™ non-toxic dye

ChromaLIVE™ is the ideal non-toxic dye and leading technology for image-based profiling. Instead of using multiple dyes and having to fix cells as in cell painting, ChromaLIVE relies on live-cell imaging to evaluate cells in...
Protocol - ChromaLIVE™ Deep Red non-toxic dye

Protocol - ChromaLIVE™ Deep Red non-toxic dye

Explore ChromaLIVE™ Deep Red, the same as our original ChromaLIVE, but with different spectral properties, allowing compatibility with NucleoLIVE non-toxic nuclear dye.  Learn its simple protocol, instrument compatibility and how to optimize your cell imaging...
ChromaLIVE Deep Red and NucleoLIVE Red for Live Cell Painting and Phenotypic Profiling

ChromaLIVE Deep Red and NucleoLIVE Red for Live Cell Painting and Phenotypic Profiling

Explore this technical note introducing ChromaLIVE™ Deep Red, a novel non-toxic dye optimized for compatibility with NucleoLIVE™ Red. This new variation of our signature ChromaLIVE™ stain addresses limitations in traditional endpoint high-content screening and cell...
How does ChromaLIVE™ non-toxic dye work?

How does ChromaLIVE™ non-toxic dye work?

ChromaLIVE™ is a non-toxic live-cell dye that operates through a unique molecular rotor mechanism. It enables high-content phenotypic profiling without perturbing cells. Instead of binding to specific biomarkers like traditional stains, ChromaLIVE passively incorporates into...
Immune co-culture with ChromaLIVE™ non-toxic dye: monitoring t-cell mediated cancer cell death

Immune co-culture with ChromaLIVE™ non-toxic dye: monitoring t-cell mediated cancer cell death

Discover new insights into Immune Cell Killing (ICK) assays with this application note that describes a novel application for ChromaLIVE™, a non-toxic dye used in live-cell imaging to provide continuous and quantitative monitoring of effector-target...
Sartorius application note: ChromaLIVE™ non-toxic dye and Incucyte® live-cell analysis system for live-cell imaging

Sartorius application note: ChromaLIVE™ non-toxic dye and Incucyte® live-cell analysis system for live-cell imaging

Unlock new compound insights in long-term live-cell assays by combining ChromaLIVE™ Non-Toxic Dye with The Incucyte® Live-Cell Analysis System. This application note, developed in collaboration with Sartorius, guides users on leveraging these two live-cell technologies...
SLAS poster 2025 - Deconvoluting cell death mechanisms with ChromaLIVE™ at Merck: a comparison with cell painting

SLAS poster 2025 - Deconvoluting cell death mechanisms with ChromaLIVE™ at Merck: a comparison with cell painting

Explore our collaboration with Merck! Our poster, "Morphological Profiling: Comparing Cell Painting and Live Cell Painting for Deconvoluting Cellular Toxicity Kinetics and Types of Cell Death Mechanisms in High-Throughput", showcases ChromaLIVE™. This study, utilizing Merck's...
SLAS poster 2025 - ChromaLIVE differentiates drug mechanisms in 3D culture with Yokogawa's high-content imager

SLAS poster 2025 - ChromaLIVE differentiates drug mechanisms in 3D culture with Yokogawa's high-content imager

This poster, a collaboration with Yokogawa and SUN Bioscience, showcases an innovative workflow for kinetic morphological profiling of live 3D spheroid models. Learn how ChromaLIVE™ Live Cell Painting assay provides non-toxic staining of live cells...
Live cell painting vs fixed cell painting:  phenotypic profiling with ChromaLIVE™ non-toxic dye and traditional cell painting

Live cell painting vs fixed cell painting: phenotypic profiling with ChromaLIVE™ non-toxic dye and traditional cell painting

Discover how ChromaLIVE™ redefines Live Cell Painting with unsurpassed performance for phenotypic profiling. This technical note showcases ChromaLIVE™ as a non-toxic dye that excels in live-cell imaging, boosting bioactive compound detection and minimizing false predictions...
SBI2 poster 2024 -  Live cell painting with ChromaLIVE™: Identifying transient phenotypes and discriminating colocalizing compounds for drug discovery

SBI2 poster 2024 - Live cell painting with ChromaLIVE™: Identifying transient phenotypes and discriminating colocalizing compounds for drug discovery

An Exploration Of Time-Dependent Phenotypic Changes For Enhanced Drug Discovery

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