Discover how ChromaLIVE™ redefines Live Cell Painting with unsurpassed performance for phenotypic profiling. This technical note showcases ChromaLIVE™ as a non-toxic dye that excels in live-cell imaging, boosting bioactive compound detection and minimizing false predictions...

An Exploration Of Time-Dependent Phenotypic Changes For Enhanced Drug Discovery

Here is a poster presented at SBI2 in collaboration with: Mayo Clinic. This poster reveals how NucleoLIVE™, our non-toxic biocompatible nuclear probe, is designed to study long-term changes of cell populations. It addresses the limitations...

ELRIG 2024 Poster - Live Cell Painting: An exploration of time-dependent phenotypic changes for enhanced drug discovery

  Explore cellular phenotypic profiling by combining live-cell imaging and cell painting techniques, leveraging ChromaLIVE non-toxic dye. This innovative approach applies cell painting technology in live cells to measure dynamic phenotypic changes, overcoming the need...

  This document outlines the general workflow for Live Cell Painting use cases, focusing on the methodology for analysis of ChromaLIVE™ data: Image Analysis: Cells are segmented and features extracted. Data processing: Features are transformed...

  Explore this poster presented at SBI2 by the Broad Institute of MIT and Harvard, a project where Saguaro Biosciences contributed the dyes and guidance for their use. This study focuses on the "Evaluation of...

  Here's what ChromaLIVE can be used for in Live Cell Painting applications: This powerful tool reveals time-dependent phenotypic changes in compound-treated cells. Developed as a multi-chromatic, non-toxic dye designed for live-cell imaging, ChromaLIVE addresses the limitations...

  This poster focuses on Live Cell Painting for probing in vitro compound toxicity in high-content screens with one of our non-toxic, mix-and-read method with ChromaLIVE. It highlights how it offers the advantage of conducting image-based profiling...

Do you have questions about our non-toxic dye? Whether it's about its live-cell imaging capabilities, live-cell assay applications, high-content imaging settings, image-based profiling analysis, or even comparisons to Cell Painting, see our FAQ here.