This work presents AutoHCS™, an AI-based tool for scoring high-content imaging results in morphological clustering that predicts mechanisms of action (MoA). Automating the detection and scoring of phenotypic responses, AutoHCS enables robust phenotypic profilingand predicts MoA,...

  This poster presents a novel approach for quantifying apoptosis in live cells. It introduces ChromaLIVE, our non-toxic dye designed for live-cell imaging and automated AI analysis, which addresses the limitations of traditional fixed-cell methods...

  This technical note is a guide providing guidance on imaging ChromaLIVE on the Yokogawa CQ1 high-content imaging system. It details the necessary steps to create custom settings for optimal imaging of live samples with...

  This technical note provides step-by-step instructions for imaging ChromaLIVE, a multi-chromatic live-cell imaging dye, on the ImageXpress Micro Confocal (IXM Confocal) high-content imaging systems. It also details how to create custom settings for optimal imaging of...

  Explore this technical note, a guide providing step-by-step instructions for imaging ChromaLIVE on the Opera Phenix and Opera Phenix Plus high-content imaging systems. This document details how to create custom settings for optimal imaging of live samples...

  Discover the extensive compatibility of our ChromaLIVE non-toxic dye with a wide range of laboratory instruments. This comprehensive list provides essential settings for various manufacturers, including Molecular Devices, PerkinElmer / Revvity and Yokogawa, as...

  This poster is a study on Live Cell Painting, showcasing drug responses in human primary patient cells with our new non-toxic dye. It presents a novel mix-and-read and non-toxic dye (ChromaLIVE), enabling the first...

This work highlights a novel fluorescent non-toxic dye (ChromaLIVE), enabling real-time phenotypic profiling in live cells and the quantification of disease-relevant phenotypes like apoptosis, autophagy, and ER stress. ChromaLIVE's unique properties, such as its multi-chromatic...

  Explore this tutorial on Metadata Integration for CellProfiler, crucial for linking data in Live Cell Painting analysis. This guide details how CellProfiler's Metadata module allows researchers to extract and manage vital image information (metadata)...