Explore this poster presented at SLAS 2024, a significant collaborative effort involving Saguaro Technologies, Sunnybrook Research Institute, IRIC - Université de Montreal, Plexium and contributions from the Broad Institute of MIT and Harvard. This work focuses...

This work presents AutoHCS™, an AI-based tool for scoring high-content imaging results in morphological clustering that predicts mechanisms of action (MoA). Automating the detection and scoring of phenotypic responses, AutoHCS enables robust phenotypic profilingand predicts MoA,...

  This poster presents a novel approach for quantifying apoptosis in live cells. It introduces ChromaLIVE, our non-toxic dye designed for live-cell imaging and automated AI analysis, which addresses the limitations of traditional fixed-cell methods...

  This technical note is a guide providing guidance on imaging ChromaLIVE on the Yokogawa CQ1 high-content imaging system. It details the necessary steps to create custom settings for optimal imaging of live samples with...

  This technical note provides step-by-step instructions for imaging ChromaLIVE, a multi-chromatic live-cell imaging dye, on the ImageXpress Micro Confocal (IXM Confocal) high-content imaging systems. It also details how to create custom settings for optimal imaging of...

  Explore this technical note, a guide providing step-by-step instructions for imaging ChromaLIVE on the Opera Phenix and Opera Phenix Plus high-content imaging systems. This document details how to create custom settings for optimal imaging of live samples...

  Discover the extensive compatibility of our ChromaLIVE non-toxic dye with a wide range of laboratory instruments. This comprehensive list provides essential settings for various manufacturers, including Molecular Devices, PerkinElmer / Revvity and Yokogawa, as...

  This poster is a study on Live Cell Painting, showcasing drug responses in human primary patient cells with our new non-toxic dye. It presents a novel mix-and-read and non-toxic dye (ChromaLIVE), enabling the first...

This work highlights a novel fluorescent non-toxic dye (ChromaLIVE), enabling real-time phenotypic profiling in live cells and the quantification of disease-relevant phenotypes like apoptosis, autophagy, and ER stress. ChromaLIVE's unique properties, such as its multi-chromatic...

  Explore this standard protocol for 3D cell cultures using ChromaLIVE non-toxic dye. This detailed guide outlines the steps needed to leverage ChromaLIVE for time-dependent phenotypic changes in 3D cell models. As a multi-chromatic live-cell...